Gianluca Lucchese MD PhD

Gianluca Lucchese MD PhD was appointed consultant cardiac and mitral surgeon at St Thomas’ Hospital in 2016. Before his recruitment to London, Gianluca had a comprehensive training in cardiac surgery in Italy and UK, including congenital cardiac, transplantation and mechanical circulatory support.

Over the last years he has focused on maximising his expertise on mitral and aortic valve repair surgery and complex aortic surgery with particular interest in the valve-sparing aortic root replacement. Also, he has pursued a specific interest in minimally invasive valvular surgery and trans-catheter valve implantation (such as TAVI), which have now become a consistent part of his surgical competences.

Research interests concentrate on the biochemical pathways of myocardial hypertrophy and myocardial protection, the hemodynamic properties of the aortic root (valve-sparing aortic root replacement, Ross operation) and the treatment of valvular heart disease with particular attention to the isolated tricuspid valve dysfunction.

Surgical interests

Minimally invasive valvular surgery

Reparative/reconstructive valvular surgery

Trans-catheter valvular implantation

Valve-sparing aortic root replacement surgery

Grown-up congenital heart disease (GUCH)

Research Interests

Myocardial Protection

Heart Remodelling

Ross Operation

Valvular heart disease

Isolated tricuspid valve dysfunction

STAT Proteins

Publications (related to valve disease)

Cannata S, Freitas D, Lucchese G, Frigiola A, Hancock J, Head C, Young C, Prendergast B, Redwood S. Transcatheter Aortic Valve Replacement for Severe Aortic Regurgitation in Singleton-Merten Syndrome.  JACC Cardiovasc Interv. 2018; 11(21):e173-e174.

Lucchese G, Montarello N, Bapat, V. A Modified Single-Puncture Technique for Transcatheter Aortic Valve Implantation in Patients without Peripheral Vascular Access.  Thorac Cardiovasc Surg. 2017; 65(3):231-233.

Lucchese G, Rossetti L, Faggian G, Luciani GB. Long-Term Follow-Up Study of Temporary Tricuspid Valve Detachment as Approach to VSD Repair without Consequent Tricuspid Dysfunction. Tex Heart Inst J 2016; 43(5): 392-396.

Luciani GB, Lucchese G, Carotti A, Brancaccio G, Abbruzzese P, Caianiello G, Galletti L, Gargiulo GD, Marianeschi SM, Mazzucco A, Faggian G, Murzi B, Pace Napoleone C, Pozzi M, Zannini L, Frigiola A. Two decades of experience with the Ross operation in neonates, infants and children from the Italian Paediatric Ross Registry. Heart. 2014; 100(24):1954-9.

Luciani GB, Lucchese G. Minimal-access median sternotomy for aortic valve replacement. Journal of thoracic disease 2013, 5 (Suppl 6), S650–S653.

Luciani GB, De Rita F, Lucchese G, Hila, D, Rungatscher A, Faggian G, Mazzucco A. Repair of congenitally dysplastic aortic valve by bicuspidization: mid-term results. Ann Thorac Surg. 2012; 94(4):1173-9.

Giovanni Battista Luciani, Gianluca Lucchese, Fabrizio De Rita, Giovanni Puppini, Giuseppe Faggian, Alessandro Mazzucco. Reparative Surgery of the Pulmonary Autograft: Experience With Ross Reoperations. Eur J Cardiothorac Surg. 2012; 41(6):1309-15.

G. Davoli, L. Muzzi, G. Lucchese, N. Uricchio, M. Chiavarelli. Large Left Atrial Myxoma with Severe Mitral Regurgitation. The Inverted T-Shaped Biatrial Incision Revisited. Tex Heart Inst J. 2006; 33(1):51–53.