Mike Marber is a physician scientist with basic research interests in the processes causing heart muscle injury and clinical interests in the care of patients with impaired heart function.
Mike Marber graduated from the Middlesex Hospital Medical School, London in 1984 having intercalated a BSc in Biophysics. After clinical training at the Brompton, St Peter’s and St George’s Hospitals he completed a PhD in physiology at University College London and postdoctoral training at University of California, San Diego. In 1996 he was appointed as a Senior Lecturer at King’s College London & Consultant Cardiologist as Guy’s and St Thomas’ NHS Trust he was subsequently promoted to Professor of Cardiology in 1999.
Mike Marber leads an interdisciplinary research group with interests in biomarkers of myocardial injury and drug discovery focusing on heart failure. Translational efforts focus on using cardiac myosin-binding protein C (cMyC) as a circulating biomarker indicating heart distress and finding small molecules to disrupt the interaction between p38α mitogen-activated protein kinase (p38α) and TGF-beta activated kinase 1 binding protein 1 (TAB1). The interaction between these proteins aggravates cardiac injury under a variety of conditions. Mike Marber has published extensively on these topics and has an H-index of 64.